Best Leaky Gut Supplements (2022)

Everyone has the goal of leading a joyful and healthy life. However, there are times when troubles in life arise, which both upset us and contribute to our lousy state.

People who suffer from Leaky gut syndrome typically experience overfatigue and distress due to leaking toxins and other bacteria from their intestines into their bloodstreams. This is harmful to the individual’s health and can be traced back to the condition that causes Leaky gut syndrome.

Unfortunately, Leaky Gut Syndrome is a condition that, unlike other illnesses, cannot be cured. Instead, the only thing that can be done to treat it is to minimize the symptoms it causes in the digestive system. Therefore, we have compiled a list of the most effective supplements to alleviate the symptoms produced by leaky gut syndrome.

The Best Leaky Gut Supplements in 2022

Below is a list of the best leaky gut supplements available:

  • Viscera-3
  • Gundry MD Bio Complete 3
  • Unify Multi-GI 5
  • Microbiome Plus Gastrointestinal
  • Peak BioBoost (Peak Biome)
  • ActivatedYou Morning Complete
  • BioTrust Gut Reg
  • BiOptimizers Biome Breakthrough
  • Gundry MD Total Restore
  • 1MD GutMD
  • Amy Myers MD Leaky Gut Revive



Viscera-3 is a dietary supplement that improves the health of your digestive system as a whole and fortifies your microbiota. It is a postbiotic that removes toxins and germs from your stomach, putting an end to bloating and gas while ensuring that your stools are well-formed. It may also reduce the circumference of your abdomen by a few inches as a side effect of eliminating bloating.

SANE Solution, which was established in 2013 and is based in Bellevue, Washington, is the enterprise that is responsible for the production of the Viscera-3 PostBiotic supplement. They provide dietary supplements in addition to online nutritional tools and coaching services. They offered several items that helped with digestive health and weight loss.

The healthy postbiotic compounds that Viscera-3 delivers to the lower colon help improve gut health and coat the walls of the digestive tract with beneficial bacteria. It encourages the regular recycling of the tissues in the digestive tract, which improves the health of the digestive system.

The alleviation of symptoms such as gas, bloating, and constipation may also result from this. A study published in the journal Nutrients looked at how postbiotics go one step farther than prebiotics and probiotics.

The decrease in bloating may help reduce the abdomen’s size. The product also contains additional components, such as chromium, that can assist with burning fat and reducing overall body weight. According to findings published in the Journal of Food and Nutrition Research, chromium has a beneficial effect on the regulation of metabolism and the body’s general health.

The following is a list of some of the most important active components in Viscera-3:

Pomegranate Fruit Extract

This fruit is helpful in the intestines because it has a high concentration of anti-inflammatory characteristics, which reduces swelling. It might be beneficial in treating digestive diseases such as ulcerative colitis.

Additionally, it stimulates mitophagy, which is the process by which cells start the process of recycling themselves.

Grape Seed Extract

It has powerful healing capabilities and is used in treating various illnesses. In addition, it has potent antioxidants, which help fortify the immune system, heal damage, and, in particular, calm the lining of the stomach. The influence of grape seeds on several biochemical markers was the subject of a recent review published in the journal Molecules.


Magnesium is a vital element involved in over 300 enzymatic activities. It’s crucial because of its function in these reactions. It encourages good bowel motions by helping the muscle fibers to contract more effectively. This laxative effect assists in cleansing the body.

Take three capsules of Viscera-3 daily, preferably upon waking up in the morning. This is the suggested dose. Under no circumstances should the dose be increased above what is recommended.

Sane Solutions, the company that makes Viscera-3 Supplements, is widely acknowledged as an ethical business producing good products. It is a good supplement, and there is a lot of demand for it on the market. Reviews of the Viscera-3 Supplement make it abundantly clear that this product is an accurate representation of its claims.

Gundry MD Bio Complete 3


This organic vitamin, known as Bio Complete 3, includes a prebiotic, a probiotic, and a postbiotic, all packaged into one convenient package. It does this by removing waste from the intestines and encouraging regular bowel movements, which are beneficial to digestive health.

It can alleviate unpleasant symptoms such as constipation, gas, and diarrhea and lessen bloating. Bio Complete 3 may help people lose weight by reducing their cravings for unhealthy foods and making them feel fuller for extended periods. It also gives more energy for your body to use.

A business that goes by the name Gundry MD and is based in Beverly Hills, California, is the one responsible for producing Gundry MD Bio Complete 3. Dr. Stephen Gundry, a practicing physician, established the organization in 2002.

Before that, he had spent the preceding decade doing in-depth research on the microbiome at his center for regenerative medicine. The company has made organic supplements that are beneficial for one’s health and well-being as well as immunity and, in particular, digestive health.

The product is composed of probiotics, which assist in maintaining a healthy microbiome in the gut and fill the walls of the digestive tract with beneficial bacteria.

In addition, they include prebiotics, which are food for the healthy bacteria in the gut and helps maintain general gut health. This soothes stomach problems such as gas, bloating, and diarrhea which may be uncomfortable. Postbiotics can mend a leaky gut and reduce stomach swelling, which may help alleviate bloating. In addition to this, they improve the function of the immune system.

These components may also contribute to the maintenance of good stool motions. In addition, decontaminating the digestive tract might result in increased energy levels.


Both a postbiotic and prebiotic may feed the beneficial bacteria in your stomach, maintain a healthy balance in your gut microbiota, and improve your digestive health. Guar gum is another name for this substance: bean fiber from the guar bean. In addition, it helps enhance mineral absorption and may inhibit hunger, all of which contribute to weight reduction.

Bacillus Coagulans

A probiotic is also a bacterium that produces lactic acid and is regarded as beneficial bacteria. It helps maintain a healthy balance of the microorganisms in the gut by lining the intestinal walls with beneficial bacteria. It has been shown to alleviate digestive problems such as bloating, stomach distress, and diarrhea.


Refers to a group of short-chain fatty acids that operate as prebiotics. This means that they provide food for the beneficial bacteria that live in the gut, which in turn helps to enhance digestion and maintain digestive health. Tributyrin is the Corebiome, and it contains butyrate, which can alter gut flora and promote colon health.

Unify Multi-GI 5


The digestive support supplement, Multi-GI 5, employs an innovative mix. It is explicitly designed to assist in the promotion of good digestion, the development of body energy, and the improvement of the management of weight loss. In addition, it may play a part in maintaining a healthy balance of gut flora and a better and healthier GI lining, both of which are necessary for a comprehensive restoration of bodily health.

The product manufacturer claims it contains 12 different potent and quality-tested gut-health enhancers to guarantee that it is both risk-free and practical. It has been suggested by the company that makes Multi- GI-5 that using this supplement might successfully revive your digestive system, thereby assisting you in achieving an overall healthy body.

The combination of substances used to make up Multi-GI-5 is intended to make its benefits more bioavailable to the body. Consuming the Multi-GI 5 supplement as advised raises the levels of crucial nutrients in your body and, as a result, may provide support for the digestive tract. This is a straightforward explanation of what this implies.

It is worthy to remark that while this supplement has been in your system, it calms the pain experienced in the gastrointestinal tract, which in turn promotes the health of the gut lining. The manufacturer of the product argues, in support of the product’s approach to enhancing general health, that a healthy body starts in the gut and that this is one of the reasons why the product could be helpful.

The possibility that Multi-GI 5 might improve bioavailability indicates that taking it can speed up the process by which your body absorbs the essential nutrients. It alleviates the pain associated with frequent gastrointestinal issues and promotes a healthy stomach lining. The following are some of the vital components that go into the production of Multi-GI 5:

Magnesium Beta-Hydroxybutyrate

Often known as Beta, it is an exogenous ketone salt believed to promote ketogenic diet tolerance. This component is included in the product Keto Vantage. Reports have shown that Magnesium BHB may encourage weight management and fitness and boost performance. The Journal of Nutrition and Metabolism states that these benefits can occur with or without dietary restrictions.

Fermented L-Glutamine

A powerful amino acid that is said to work as a protective layer of the intestinal walls, this ingredient is one of the critical components of this supplement. Glutamine is a particular nutrient that serves as a source of fuel for the control of cell growth, metabolism, and the preservation of intestinal barrier function.

Hydroxybutyrate (BHB)

This substance provides your body with what it needs energy that is accountable for supplying fuel to human muscles and the brain. BHB may be used to keep the body’s fitness levels optimal.

Microbiome Plus Gastrointestinal


Another excellent product offered by the microbiome, the Microbiome Plus+ Gastrointestinal combo, is consistently ranked among the company’s most popular offerings.

This contains both probiotic and prebiotic fibers, which are the two types of fibers considered to be of the utmost importance.

Your gut health will improve due to taking Microbiome Plus+ Gastrointestinal Combo, and you will have minor discomfort from indigestion.

Microbiome Plus+ It has been shown in clinical studies that probiotics reduce LDL cholesterol levels, making them essential in maintaining good heart health.

It has been shown that reducing LDL cholesterol levels offers several health advantages for the heart. Your cardiovascular system will become more robust as a result of this.

The fact that only the most knowledgeable and skilled medical experts contributed to the creation of Microbiome Plus+ is, without a doubt, the supplement’s most notable strength. Consequently, a significant amount of investigation and study is required.

When you have a healthy stomach, the rest of your body is secured against germs and viruses that may be harmful or hazardous. Therefore, Microbiome Plus+ improves the gastrointestinal tract’s health and the overall immunity of both the body and the gastrointestinal tract to dangerous infections.

You run the risk of developing diabetes, cardiovascular disease, and even cancer if your body does not have sufficient levels of vitamin D. You need to maintain adequate levels of vitamin D, and Microbiome Plus+ can assist you in achieving this.

In my opinion, the fact that Microbiome Plus+ is so simple to apply makes it the standout feature of this product because so many competing brands need to fulfill a long list of preconditions before using their goods.

You must take it twice daily to get the most out of this supplement.

Nevertheless, we advise you to check with your primary care physician before taking any supplement, including this one. Because of the various factors at play, the primary one is that every person is an individual with their own set of physiological quirks, and some bodies may respond more slowly or differently than others.

The Microbiome Plus+ Gastrointestinal Combo is formulated with one-of-a-kind and high-quality components. Each component has its unique impact on the body’s physiology and a set of advantages.

If you can include these components in your diet regularly, then doing so is recommended, but doing so will entail financial and time commitments. You must make an investment in this supplement instead of doing that so that you may strengthen your health.

  • Microcrystalline Cellulose – It is a common vitamin component that may be found in dietary supplements. This has a beneficial influence on the workings of the body.
  • Magnesium stearate – Has a role in helping to keep food moving through the digestive tract and stomach consistently. This is being used in the medical field as well.
  • Dicalcium Phosphate is utilized to eliminate the smell the stomach and the body give out.
  • Stearic Acid – Stearic acid is responsible for the body’s ability to retain water.

Peak BioBoost (Peak Biome)


Your breakfast oatmeal or latte might benefit from adding Peak BioBoost, a dietary supplement that comes in the form of a powder. Peak Biome Inc., the company that developed this device, says that they assist people to enhance the quality of their lives by concentrating on the intestines of individuals.

The supplement known as Peak BioBoost promises to help users achieve “perfect poops,” shed unwanted pounds, and lead overall happier lives.

People 40 to 50 years old are the target demographic for Peak BioBoost.

Xylo-oligosaccharides (XOS), one of the components in this supplement, are said to perform very well in individuals over 60; hence, this product is beneficial for those over 50. This may also be utilized by those who are pretty young than this age range.

After researching Peak BioBoost, we have determined that the supplement seems to be an excellent choice for consumers. The website for it provides a significant amount of information and explains precisely what it is designed to achieve in a very understandable way.

This company decided that they sought to provide something that would be helpful to anybody who needs a gut cleanse or is experiencing any problems with the amount of time they spend in the toilet.

The brand’s founder claims he suffered from severe constipation throughout his life. He didn’t defecate for over a week at one point, and his body alerted him that he needed to go to the bathroom at a wedding ceremony.

It is believed that the reason Peak BioBoost works so effectively is that it assists in everything that is required to have “excellent stool.” Your anxiety will be reduced, which will result in your muscles and nerves being more relaxed. This product also has a very high concentration of fiber in its make-up. When you consume a diet high in fiber, you will have a more incredible amount of feces. Because fiber makes digestion more effortless, the total quantity of matter has risen.

The use of this medication is also said to boost the health of your digestive tract. If your digestive tract is functioning normally, you must have this supplement to have “perfect” and consistent bowel movements.

All of the components of this product are focused on improving digestion in some way. Combining these factors will likely give your problem the most effective and rapid solution.

The Peak BioBoost supplement is designed to aid in the regularity of your bowel movements. This product should assist your body in achieving the ideal daily balance of water and fiber, ensure that only beneficial bacteria are present in your intestines, and hasten the rate at which you pass stool.

ActivatedYou Morning Complete


The Morning Complete combination of dietary supplements is taken daily to promote complete health. The Morning Complete supplement claims to help you get your day off to a good start with only one scoop diluted in eight ounces of water or tea.

Consuming Morning Complete is simple since you only need to pour one glass of 8 ounces of water and continue your regular daily schedule as if it were any other day.

Having a healthy start to the day is possible with the aid of Morning Complete. Although it may be considered a supplement for overall health, its primary goals are to give a combination of high-quality fiber, support for brain health, care for the digestive system, and assistance in achieving balanced blood sugar levels.

However, this does not imply that the supplement is a “wonder” medicine that can heal all of your ills and make you completely healthy again. To enhance your health, however, you must take a comprehensive approach to the problem.

Some components improve the health of almost every organ, system, and function in your body.

Good for the Gut

The combination of probiotic substances and nutrients that are rich in fiber is ideal for maintaining the health of your gut. In addition, consuming green superfoods will encourage good bowel movements and the absorption of minerals.

Your immunity improves along with your gastrointestinal system’s health when properly functioning. In addition, the addition of the cellular membranes and liver support mix will allow your body to perform more effectively.

The Health of the Heart

You may anticipate a lower risk of cardiovascular and other cardiac diseases if you regularly consume Morning Complete due to its high number of anti-inflammatory and antioxidant substances. The help for maintaining normal blood sugar levels will also minimize the danger of developing diabetes, which may eventually be harmful to your heart.

Skin Health

Your skin will also stay healthy if you consume green superfoods, other antioxidants, and anti-inflammatory substances. These components defend against oxidative stress and pollutants that contribute to your skin’s aging and the harm they bring to cells.

Weight Gain Management

You can manage your food cravings and gain assistance for losing or maintaining your current weight if you take a supplement with sugar-balancing help, antioxidants, a high fiber mix, and probiotics.

If you want to use Morning Complete regularly, it is recommended that you purchase multi-packs since it will save you money in the long run. You can acquire Morning Complete with full confidence since the company offers a money-back guarantee on all purchases for ninety days.

BioTrust Gut Reg


The supplement for gut health known as BioTrust Gut Reg is a product manufactured by BioTrust. It is meant to tackle various concerns associated with digestive health, including anything from inflammation and indigestion to vomiting, mental confusion, emotional difficulties, sleep disturbances, and skin problems. These issues may all be addressed with this supplement.

Your digestive tract is linked to a wide variety of different organs and tissues in your body. You may promote a healthy digestive lining with the minerals, nutrients, herbals, and vegetables included in Gut Reg if you take the active substances in it regularly.

Gut Reg concentrates on a limited number of components given in high doses rather than trying to overwhelm you with a large variety of active chemicals. Each dosage of two capsules provides 500 milligrams of L-glutamine, 250 milligrams of ginger extract, and either 100 percent or higher of the daily recommended value for zinc and vitamin D3. Gut Reg has four active components that work together to maintain your intestinal lining in numerous ways.

BiOptimizers Biome Breakthrough


The BiOptimizers Biome Breakthrough product is a supplement for leaky gut that has a chocolate taste and was made with synbiotics, including prebiotics and probiotics, all mixed.

The Biome Breakthrough supplement from BiOptimizers may, among other things, improve general gastrointestinal health, lessen intestinal wall permeability, do away with cramping and gasses, and stimulate a healthy immunological response.

Inflammation of the gut and impaired nutrition intake are common problems for those who struggle with the leaky gut syndrome. According to the manufacturer, Biome Breakthrough can address these difficulties by enhancing nutrition retention and decreasing inflammation in the intestines.

Gundry MD Total Restore


When you take care of your stomach, you are taking care of the health of your whole body. This concept served as the inspiration for the creation of Gundry MD Total Restore.

Total Restore is a nutritional supplement developed by Gundry MD that is targeted at those who suffer from a disease known as “leaky gut” syndrome. This sickness is thought to impact many people and create symptoms ranging from mild to severe.

People who speak about having a leaky gut refer to intestinal permeability, which is the formation of pores in the wall of your intestines that may allow potentially harmful bacteria and poisons to pass through. In many people’s experiences, these digestive tract problems are brought on by lectins.

Lectins are capable of adhering to the cells in your gut and working to separate the membrane of your gut as they do so. There is no one way that a leaky gut manifests itself for different individuals; however, if you are weary, have digestive distress, painful joints, poor energy, or head fog, you may have a leaky gut.

Because it helps the lining of your gut, Total Restore was formulated to assist your body in warding off weariness, gastrointestinal distress, gas, bloating, joint pain, and even impulses for unhealthy foods. This is accomplished by reducing inflammation in your joints.

If the Gundry MD Total Restore supplement had been released on the market, consumers of health supplements would have been under a lot of pressure. There was a vast selection of dietary supplements on the market; however, many of these products included sugar or artificial sweeteners. Not only may artificial sweeteners cause harm to your health, but regular use can also lead to addiction.

On the other hand, Gundry MD Total Restore contains neither natural nor artificial sweeteners nor any added sugar. In addition, each component was meticulously chosen after considering the relevant scientific evidence. Examining the details that make-up Total Restore is the best way to get all the information you want about this product.

Read customer reviews to learn how other people’s experiences have been using it. It is not simply a gut supplement; Gundry MD Total Restore is a multi-faceted compound meant to aid and improve energy storage, support attempts to slim down, and promote a healthy gut.

According to Gundry, Total Restore may help alleviate sore muscles and joints, increase one’s energy level, and curb uncontrollable cravings for unhealthy foods.

Each container of Total Restore includes 90 capsules, which are to be consumed in conjunction with each meal for a total of 3 times each day.

According to Gundry, a user of Total Restore should feel the product’s benefits within a few days, with a more noticeable enhancement in gut and healthiness occurring after about the first two to three weeks of usage.

By reducing the quantities of endotoxin generated by bacteria, half of the components that make up Total Restore directly work to alleviate symptoms of indigestion and other problems associated with the gastrointestinal system.

Total Restore is formulated to relieve various symptoms, such as decreasing the volume of gas generated in the gut, bloatedness, constipation, and bowel problems. This product is constructed with only natural components and is intended to do so.

The fact that all of the components of Total Restore come from natural origins makes it very unlikely that the supplement would result in any adverse consequences.

Integrating Gundry MD Total Restore into your existing health regimen is straightforward. Take three capsules daily. They are not difficult to chew or swallow. You may have all three with the meal that provides the best satisfaction for you throughout the day.

The Gundry MD. The extracts included in Total Restore were chosen for their ease of digestion, allowing you to experience the supplement’s effects as early as possible. If you want to get the most out of your Total Restore supplement throughout the day, try taking it with breakfast.

The Gundry MD. Total Restore also does not include probiotic microorganisms. Total Restore uses potent substances and nutritious and comfortable chemicals for your gut.

On the other hand, Total Restore was designed to help maintain the health of your stomach. Additionally, your digestive tract serves as a habitat for beneficial microorganisms known as probiotics. Therefore, if you currently take a probiotic supplement, this may assist in reinforcing the benefits of doing so.

It consists of crab as well as shrimp. Be cautious if you suffer from an intolerance to seafood.



A nutritional supplement known as GutMD has been developed to eradicate infections, bolster the intestinal barrier, soothe the mucosal lining, and improve general gut health.

This supplement is constructed from four components that have been the subject of an extensive clinical study and demonstrated to be effective in testing. As a result, it helps prevent intestinal infections, inhibits the development of bacteria that might cause disease, and promotes the digestion of nutrients.

Digestive wall, nutrient absorption, and improved immunological health are a few other benefits of this supplement. In a broad sense, the development of gut flora is encouraged by taking this supplement.

GutMD is formulated with potent components that, when combined, maximize the body’s capacity to absorb nutrients, hence removing any possibility of experiencing gastrointestinal distress. Additionally, the lining of the digestive tract is strengthened, stopping toxins from penetrating the intestines and getting into circulation.

These powerful substances also include prebiotics, which serves as food for the beneficial bacteria that are already present in your digestive tract. The health of the stomach and digestive system is improved when these activities work together. In addition, the immune system gets strengthened with time.

Here are some of the ingredients of 1MD GutMD:


Glutamine, a form of the amino acid L-glutamine, is one of the free amino acids found in the body in the most incredible abundance. It is a crucial substrate that the cells of the digestive tract use. Glutamine has a significant role in the physiology of the intestines and the treatment of various gastrointestinal conditions. In disorders such as inflammatory conditions, glutamine intake has been thought to help treat the disease.

Acacia Fibregum

According to clinical investigations, acacia gum has become more popular as a prebiotic fiber over the last several years. It was shown that taking a supplement high in acacia fiber may reduce the number of dangerous bacteria in the gut while simultaneously raising the number of beneficial lactobacillus bacteria, demonstrating that the supplement had prebiotic effects. In addition, it was discovered that acacia gum enhances the process by which the body absorbs minerals.

GutGard (Licorice Root)

Glycyrrhiza glabra is the scientific name for the component known as GutGard (Licorice Root). It is used in the field of herbal medicine to improve the health of the gastrointestinal tract. Patients often get a prescription for licorice root because of its anti-inflammatory, demulcent, and gentle laxative properties. It is often used to treat mucosal inflammation, dryness, and ulcerations.

Consume one serving of this product daily, which consists of three capsules. Take this medication first thing in the morning before eating breakfast with a glass of water or as directed by your physician. You should hold off on eating for at least an hour.

GutMD By 1MD is a dietary supplement developed by medical professionals and intended to help build and restore the lining of the digestive tract. Additionally, it guarantees the removal of dangerous microorganisms from the digestive tract, which will result in an enhancement of both the individual’s health and the immune system as a whole.

Because it has these qualities, this supplement benefits the health of those with digestive problems.

In addition to strengthening the gut lining, GutMD improves the body’s ability to absorb nutrients and provides beneficial bacteria with prebiotics to stimulate their development. This makes digestion even better and helps prevent gastrointestinal problems from occurring.

GutMD treats problems with the gut lining systematically. GutGard, a proprietary substance extracted from licorice root, begins to function regularly during the first two weeks of treatment to alleviate stomach troubles. It accomplishes this by battling the potentially harmful bacteria found in the stomach. Acacia fiber gum and HMO CARE4U will, after 30 days, have contributed to an increase in the population of good gut bacteria and an improvement in the function of the immune system.

Amy Myers MD Leaky Gut Revive


The lining of your gut may be negatively impacted by toxins and bad diets, which can reduce the number of nutrients absorbed and make digestion more difficult. Because of a leaky gut, some people experience feelings of lethargy. Others have problems with bloating or their digestive system. It is said that if you use Leaky Gut Revive, you will be able to resolve these concerns.

The Amy Myers MD product is distributed in powder form and bulk. You take one daily serving by mixing six teaspoons of the product with one serving of juice or a protein shake. Dr. Amy Myers identifies the taste as “light” and says it is “not unpleasant.” Some people like to combine the powder with juice or other tastes with more robust flavors, while others prefer to mix it with simple water.

Leaky Gut Revive may be one of Amy Myers MD’s most popular digestive supplements. The supplement asserts that it will promote relief for people suffering from a leaky gut and improve your overall digestive health, enabling you to enhance your immunity, cure digestive problems, and take pleasure in various other advantages.

The Best Leaky Gut Supplements in 2022 Conclusion

Inflammation in the digestive tract may cause many unwelcome health symptoms, including persistent constipation, exhaustion, and menstruation problems.

However, making some adjustments to both your food and your lifestyle could be all that is required to make you better your digestive health and get better control over these symptoms.

Because this illness is both excruciating and hazardous, you must prioritize taking care of your health as much as possible. Additionally, you must schedule frequent appointments with your physician and try a top leaky gut supplement today!


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