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Best Immune System Boosters: Top Immunity Supplements 2022

Your immunity decides how well you are going to live your life and protect yourself against various viral and bacterial infections. Your immune system works as your body’s natural defense mechanism against dangerous illnesses and diseases.

The sound your immune system is, the healthier you will be. Some people are naturally well-built and have an excellent working immune system. Others focus on exercising regularly and incorporating good lifestyle habits to improve their body’s immune system.

However, many people rely on the best immunity boosters to help boost their daily immunity levels. Whether it is a Vitamin C supplement, zinc dosage, herbal, or other plant-based extracts, all these compounds are scientifically proven to help improve your overall immunity score.

We spent thousands of hours researching, finding, and then compiling the list of Best Immunity Boosters that genuinely support your immunity levels. Keep reading our guide to discover some of the most highly-ranked and best immune boosters you should consider buying in 2021.

The Best Immune System Supplements in 2021

Our editorial team tried and tested several immune boosters to come up with the best ones for you. We read numerous laboratory reports, reached out to manufacturers, and researched extensively to formulate this list of the best immunity boosters of 2021.

VitaPost Immune Support Supports immune cells to boost immunity
Mushroom DefenseStrengthen bones and muscles
VitaPost Immune Complex Produces more immune cells to support immune health
Zenith Labs Nano C Support immunity to protect the body from various health issues
Epishield Plus Protects the body from viral and bacterial infections
Advanced Bionutritionals Resistol Combat symptoms of various infectious diseases
Organixx 7M Increases immune health by providing antioxidant ingredients
BioShield MD Alleviate stress and other health issues
VitaPost Turmeric and Ginger Defeat with pain and inflammation
Immuno Defense4X Enhance immune function by naturally producing new immune cells
Doctor G’s Q-Ion Immune Defense Reduces inflammation and increases white blood cells
Immunity 911Enhance immune system
Immunity Formulas Immune Support Fast-acting formula to support immune health

VitaPost Immune Support


VitaPost Immune Support is an immunity-boosting supplement that delivers a range of botanical extracts to support immunity and boost immune system function. According to VitaPost’s website, the herbal extracts, vitamins, powerful antioxidant elements, and minerals present in the Immune Support supplement can help you develop a healthy immune system.

The supplement comes with ingredients with antioxidant properties to significantly boost immunity levels.

Ingredients Vitamin E, Green Tea extract, beta Glucans, Graviola Leaf, Vitamin E, Pine Bark Extract, Mushroom, and herbal complex
Key Highlights
  • Boost your immune system naturally
  • Protects your body from infectious diseases
  • Lower blood pressure and high blood sugar level
  • Prevent colds and other viral infections
  • Money-Back Guarantee30 days
    Price $14

    Mushroom Defense


    Mushroom Defense is another immunity booster that you should consider purchasing this year. Mushrooms are well-known for supporting your overall immune function. According to research studies, mushrooms can fight against fatigue and boost cognitive health. Some studies say mushrooms can even enhance your memory and sharpen your focus. Mushroom Defense’s manufacturers advertise themselves as a way to protect against viral and bacterial infections while also boosting your energy and producing antibodies to fight disease.

    Ingredients Turkey tail, Agaricus blazei, reishi, lion’s mane, shiitake, Chaga, maitake, and cordyceps
    Key Highlights
  • Minimize stress and anxiety
  • Decrease inflammation and reduce various body pain
  • It helps in building a robust immune system
  • Boost immune response against immune dysfunction
  • Money-Back Guarantee67 days
    Price $60

    VitaPost Immune Complex


    VitaPost Immune Complex is the second immunity formula produced by VitaPost. VitaPost Immune Complex shares many of its features with the Immune Support supplement by the same brand. One of the most resembling factors in these supplements is the presence of proven ingredients with anti-inflammatory effects and antioxidant properties.

    According to various studies, this supplement uses unique ingredients that help in combating the symptoms of autoimmune disorders, common cold, and many more issues. Also, probiotics are the beneficial bacteria present in your intestinal tract, and act as a strong foothold for your entire immune system.

    Ingredients Elderberry, Turmeric, Echinacea, Garlic powder, and Vitamin C
    Key Highlights
  • Produces more white blood cells to boost the body’s natural defenses
  • Boost cardiovascular health
  • Triggers immune response towards infectious diseases and viral infections.
  • Build a strong immune system
  • Money-Back Guarantee30 days
    Price $12

    Zenith Labs Nano C


    Dr. Ryan Shelton from Zenith Labs developed a Vitamin C formula called Nano C Immune Support. You can experience the goodness of Vitamin C in all of the supplements mentioned on this list. However, Dr. Shelton’s formula differentiates itself because it is a unique, bioavailable version of Vitamin C in the form of a tincture that we do not commonly see in other supplements.

    Vitamin C is one of the best antioxidants available in our natural environment. Nano C can strengthen the human immune system and speed up the absorption process using nanotechnology while promoting the antibodies’ production and supporting fast recovery from viral infection and various infectious diseases.

    Ingredients Vitamin C, Vitamin E, and other essential nutrients
    Key Highlights
  • Boost your Immune system by producing more immune cells ‘
  • Treats upper respiratory infections
  • Reduces the risk of heart disease
  • Improve overall health and well being
  • Money-Back Guarantee60 days
    Price $49

    Epishield Plus


    Simple Promise manufactures its Immunity Supplement called Epishield Plus, a dietary supplement. This formula claims to boost your immunity levels within two hours of consuming it. This supplement contains ingredients similar to other Immune Boosters. Epishield Plus also has an unusual ingredient that we don’t often see with other formulas: fermented yeast. This fermented yeast present in Simple Promise’s solution can purportedly help you maintain a strong and healthy immune system.

    Ingredients Epicor, Vitamin C, Vitamin D, Chaga Mushroom, and Shiitake mushroom extracts
    Key Highlights
  • Boost immune response towards viral infectious diseases
  • Protects you from the common cold and various illnesses
  • Regulate stress hormones for the better immune system
  • Helps in wound healing
  • Money-Back Guarantee365 days
    Price $49

    Advanced Bionutritionals Resistol


    Advanced Bionutritionals Resistol advertises its supplement- Resistol, as a nutritious supplement that can help to increase immunity naturally and effectively to deal with various health conditions. It is one of the best immune boosters that promotes overall health and well-being. Many people consume this immune booster due to its unique ingredients to improve immunity.

    Ingredients Andrographis, eleuthero, Platycodon, prickly chaff flower, and licorice
    Key Highlights
  • Reduces invading pathogens by producing more immune cells
  • Boost immune system to allow your body to cope with stress
  • Promotes cognitive health
  • Increases white blood cells for better immune system function
  • Money-Back Guarantee14 days
    Price $30

    Organixx 7M


    Organixx 7M Price uses mushroom extracts and other beneficial ingredients to help boost your immune system by producing immune cells. This formula contains mushroom extracts blended with beta-glucans that provide antioxidant and anti-inflammatory benefits reportedly.

    According to the manufacturer, consuming their formula daily promotes your immune function, healthy digestion, respiratory health and supports anti-inflammation, all while protecting you from dangerous illnesses and diseases.

    Ingredients Shiitake, Chaga, Maitake, Lion’s Mane, Cordyceps, Reishi, and Turkey Tail
    Key Highlights
  • Boost immune function
  • Promotes immune system cells
  • Alleviate chronic stress
  • Enhance immune responses
  • Money-Back Guarantee365 days
    Price $55

    BioShield MD


    With BioShield MD, you can give yourself a supplement that is responsible for boosting immunity by supporting natural stamina, mental and physical health.

    We have chosen Bioshield MD as one of the best immune boosters for the right reasons: the most influential is its delivery of the best and proven ingredients at effective dosages. The ingredients present in Bioshield MD are rich in antioxidants and flavonoids that are known to support your immune systems in various ways.

    Ingredients Cocoa Extract, green tea extract, Curcumin Extract, Tart Cherry Extract, Boswellia Serrata, and Resveratrol
    Key Highlights
  • Minimize stress
  • Decrease inflammation by increasing immune cells
  • Promote overall wellness
  • Recommended by Medical doctors
  • Money-Back Guarantee365 days
    Price $50

    VitaPost Turmeric and Ginger


    VitaPost Turmeric and Ginger is the third and final immunity supplement on our list by VitaPost. This formula is a premium mix of BioPerine with other healthy ingredients that promote a healthy immune system and joint health by providing your body with a high dosage of antioxidants. Many people consume ginger and turmeric as supplements daily to help support their overall well-being. Both of these ingredients are two of the most popular superfoods in the Immunity Industry.

    Ingredients Ginger extract, bell peppers, and Organic Turmeric
    Key Highlights
  • Reduces chronic stress
  • Boost white blood cells
  • Provides various health benefits
  • Protects viral infections
  • Money-Back Guarantee30 days
    Price $23.95

    Immuno Defense 4x


    Defense 4x is another nutritious immunity supplement manufactured by JayLab Pro. This natural supplement uses only four ingredients to support your immune system. Immuno Defense 4x is also the second supplement on our list that contains EpiCor; this is a type of dried yeast extract studied scientifically for its impact on immunity.

    Ingredients Quercetin, Vitamin D, Whole Food Fermentate, and Bromelain
    Key Highlights
  • Reduces pain and inflammation
  • Responsible for boosting immunity
  • Combat infectious diseases
  • Boost immune function
  • Money-Back Guarantee60 days
    Price $45

    Doctor G’s Q-Ion Immune Defense


    Doctor G’s Q-Ion Immune Defense is one of the few immunity boosters on our list that claims to be medically backed by doctors; this means at least one practicing doctor has approved its usage for better immune function. The creators of the Q-Ion Immune Defense formula claim that their supplement acts as a potent anti-inflammatory supplement.

    Ingredients Bromelain, Zinc, green tea extract, Camellia Sinensis Extract, and Quercetin
    Key Highlights
  • Protects from harmful pathogens
  • Combat stress and anxiety
  • Offer quality sleep and mood
  • Boost respiratory health
  • Money-Back Guarantee60 days
    Price $80

    Immunity 911


    Immunity 911 is an Immunity enhancement supplement that PhytAge Labs developed. This supplement comes power-packed with some of the most potent ingredients that strengthen your immunity levels. This factor makes it a top choice for anyone looking to support their body’s defense mechanism against infections.

    Ingredients Himalayan Raspberry, Graviola Leaf, Mushroom Blend, Himalayan Pomegranate, and Olive Leaf
    Key Highlights
  • Safeguard body from various infections
  • Boost energy level for better physical performance
  • Manages stress hormones to maintain good immunity
  • Produces more immune cells to support immunity
  • Money-Back Guarantee90 days
    Price $70

    Immunity Formulas Immune Support


    Immunity Formulas Immune Support claims to contain therapeutic-level herbal essential oils that can professedly cure all types of immunity and viral problems. According to the website of Immunity Formulas, Immune Support helps build your natural defense while boosting your body’s overall immunity. It also sanitizes the surfaces, disinfects, and purifies the air alongside providing other benefits.

    Ingredients Peppermint, Turmeric, Cinnamon, Lemon, Bioperine, and Oregano.
    Key Highlights
  • Purifies the surroundings
  • Promote healthy lifestyle
  • Produces immunity cells to boost immunity
  • Enhance energy level
  • Money-Back Guarantee90 days
    Price $60

    How We Ranked the Best Immunity Boosters

    Every immune support supplement available in the market today claims to support a healthy immune function within your body. However, only some of these supplements contain proven ingredients. Others are just a mixture of weird herbal extracts supporting themselves with a few scientific studies. However, to prepare this list of best immunity boosters for you, we used the following ranking metrics to help separate our team from the worst and the best immunity support supplements. These factors are as follows:

    Scientifically-proven Ingredients

    For immunity boosting, certain ingredients come with a piece of scientific evidence to help deliver life-altering benefits for your immune system. For example, zinc, probiotics, Vitamin C, D, and elderberry extract are known to improve your immune health substantially. There are several research studies conducted that depict the impact of these ingredients on immunity in a positive light. For this list, we preferred supplements that came with a scientifically proven ingredient list known to benefit your immune system.

    Effective Dosage Options

    Some Immunity support supplements use the right ingredients but offer the wrong dosage options to their customers. In contrast, some immunity boosters contain numerous ingredients, sometimes even more than a dozen, but offer such few dosage options that their overall impact on your body’s immune system is not evident. While preparing this list for the best immunity boosters of 2021 and comparing different products, we preferred immunity support supplements that offered robust and clinically proven dosage options of all ingredients mentioned on their labels.

    Honest Advertised Health Benefits

    According to FDA regulations, supplement companies cannot claim that their product or formula can help cure certain diseases to help improve your overall health. That is against their norms. The supplement companies can only claim so much: that their product can help support your health in a particular way. It comes as a surprise that many immunity boosters have even stopped using the term “boosters.”

    Still, there are some immunity support supplements in the market today that blatantly claim to be your one-all, cure-all solution. They advertise themselves as the virtual go-to-options, going all the way in to claim that they can prevent certain diseases, even Covid-19, and provide powerful benefits.

    However, as your guides, we want to inform and lead you. We want to help you in making the right decision. As a customer, even though it gets tempting, we want you to know that such supplement companies are only making hollow claims to lure people into buying their products. But as a responsible buyer, you must know, understand, and analyze if a particular immunity booster is fit for your individual needs or not.

    We suggest you do not fall for these unproven and dishonest claims, which is why we took the load off your shoulders and did the work for you. We did not choose immunity supplement companies that made false claims to their customers, so you can rest assured that the supplements mentioned here are genuinely the best immunity boosters that you should consider buying this year.

    Manufacturing Area

    While making this list, we understood the importance of having a certified manufacturing location. For this list, we preferred supplement companies that manufactured their formulas in registered and certified facilities. It is not uncommon to see that some supplement companies often outsource their products from cheap facilities located overseas. Other companies rely upon local factories approved by the FDA and other national advisory and regulatory boards.

    The more transparency and honesty we observed in the manufacturing process, the higher we ranked that supplement company on our list. Some companies make fraudulent claims. However, we did thorough research to avoid misleading our readers and protect you from such illegal manufacturers. So, we only made it a point to include legitimate, certified, and approved manufacturing locations over those that misled people.

    Medical Advisory Board

    Some of the best immunity support supplement companies have a medical advisory board of their own. These companies have their practicing doctors and medical professionals that overlook every aspect and function of their production process. This medical advisory board either reviews or creates formulas by using their medical experience to produce the best quality immunity supplement in the market.

    It is also amusing that some supplement companies operate without medical staff or a medical advisory board. It is these companies that you have to look out for and avoid generously. Without a professional doctor or medical staff, these companies’ supplements are illegitimate and without any solid backing to support their benefits. This factor makes these formulas less compelling and less legitimate.

    However, it would help if you did not worry, as we have only compiled the list of best immunity support formulas for you. For this list, we did not choose supplement companies that operated and produced their products without the help and guidance of a medical professional. Instead, we only included immunity boosters that medical experts led, backed, and developed under the holistic guidance of a medical advisory board.

    Manufacturer’s Reputation

    Like other supplement industries, some manufacturers have only entered the immunity market to make a quick buck without caring about making a difference in people’s lives. We have seen more of this happening, especially during the Covid-19 pandemic. However, another level of trust comes with long-established manufacturers who have been working in the immunity industry for years. They are known for their high-quality immunity supplements, and they carry a long-standing well-rounded reputation, not just for the products they have created but also for the trust they have earned among the customers.

    However, for this specific list, we preferred immunity supplements produced by manufacturers with a long and well-established reputation for providing honest, high-value, and effective immunity boosters over the years, all while maintaining high-grade transparency among the users.

    Ingredient Sources

    Some immunity boosters use unique ingredients that we do not see with other supplement companies. For example, some immunity supplements will use a mix of unusual mushroom extracts, while others may go for the routine Vitamin C, E, and zinc blend.

    Most of these ingredient sources are shady and not actual. Most producers do not purchase and use the best-quality ingredients that are available on the market. These kinds of manufacturers are also very vague about the origins of their ingredients. We suggest that if you do not know a product’s origins, it is better to look for more transparent options. We have done the work for you.

    This list for the best immunity boosters of 2022 only comprises supplements that we thought were honest with their ingredient’s origins. For this list, we only preferred supplement companies that were straightforward, honest, and transparent in disclosing their ingredients’ source locations to us, and you can trust us with this list.

    Price and Value

    Some people are comfortable spending $10 for an immune support supplement. Others want to spend more and go up to $100 or more to purchase the same immunity formula. We know and very well understand that different individuals assess value differently. Some associate it with price, while others relate it to quality.

    We tried to incorporate both ends of the spectrum by understanding that different people will have different needs and preferences. No two customers are alike. So, for this specific list of best immunity boosters, while we incorporate immunity support supplements at different price ranges, we laid a great emphasis on the value that the product offered at every price range

    What Are Some Side-effects of Immunity Boosters?

    It is essential to keep in mind that every time you are following a recommended dosage instruction (either by your doctor or the immunity supplement company), you are least likely to experience any side effects of immunity boosters. This conclusion comes with a pre assumption that you are a healthy adult who is not currently under any prescribed medication.

    Legally, nutritional supplement companies often need to use ingredients and dosage options that are Generally Recognised as Safe (GRAS) by the FDA. When it comes to the most common ingredients used in immunity boosters, all of them are safe for human consumption under regular dosages. All reputable immunity supplement companies abide by this list and follow their guidelines and instructions devotedly.

    However, you may still experience a little discomfort if you have never consumed an immunity booster before, just like it happens with any new thing that you try. You may experience indigestion, bloating, nausea, or mild stomach discomfort after popping a pill of an immunity booster for the first time. It is not unusual to watch people struggle to process the supplement in a powdered, capsulated, or tableted form.

    Still, just like with any other health supplement, we always recommend that you speak with your doctor first before jumping onto a decision about consuming an immunity support supplement, especially if you have never taken one before. We advise you to always take guidance from your doctor, especially if you are undergoing any treatment or on some prescribed medication. It is for your benefit so that you do not end up making changes your body cannot afford to experience yet.

    FAQs About Immunity Support Supplements

    Q) How does immunity work in a person’s body?

    A) A healthy body is healthy because it contains a well-functional immune system which is the body’s defense mechanism to keep harmful substances at bay. Your immune response has multiple layers to it. It is not a simple concept to understand. The first layer creates a line of defense for your body against pathogens and protects you from cough, cold, reflex, or tears. The primary way in which immunity works is to ensure that no harmful substances enter the territory of your body. A healthy immune system will fight and remove foreign invaders from your body in an effective manner.

    Q) What do you mean by T Cells?

    A) Some immunity support supplements available in the market today claim to target T Cells in your body specifically. The T Cells in your body fight infections in two significant ways. There are helper ‘T’ Cells that further activate the B cells to secrete antibodies and kill all the infected target cells. The other type of T cells are known as Killer ‘T’ Cells, and they directly target and kill the infected cells without producing any antibodies.

    Q) What do you mean by antibodies?

    A) Antibodies are protein substances developed by your body’s immune system to fight infections within. Antibodies are a crucial part of the immune system. Your body always requires antibodies to fight various diseases.

    Q) What are the best vitamins available in the market today to boost your immunity?

    A) Some of the best vitamins available in the market today to boost your overall immunity levels are Vitamin C, Vitamin E, and Vitamin D. These are some of the most popular vitamins that people purchase to support their immune health. According to several research studies, all of these three ingredients can affect your immunity positively.

    Q) What do you mean by innate immunity?

    A) Innate immunity is your body’s first line of defense mechanism against pathogens or foreign invaders that try to enter your body. Some parts of innate immunity include your skin (which prevents most of the pathogens from entering your body), mucus (that is known to trap pathogens), and stomach acid (that destroys all pathogens). The enzymes present in your sweat and tears also have antibacterial properties, so we hope you take it positively the next time you sweat or cry. There are some immunity support supplements available in the market today that specifically claim to target and boost your innate immunity.

    Q) What do you mean by adaptive or acquired immunity?

    A) Adaptive or acquired immunity is the part of your body’s immune system that has learned to identify a pathogen. For example, your spleen, thymus, bone marrow, and lymph nodes all regulate this part of your immune system. Whenever these cells or organs perceive a pathogen threat near them, they create antibodies in response to that pathogen threat and therefore protect your body. A person’s adaptive or acquired immunity is as important as their innate immunity. Both of these immunities play a pivotal role in protecting your body against harmful bacteria, infections, and diseases.

    Q) What are the best foods that one should eat to boost their immunity levels?

    A) Some of the best food options you can consider and consume to boost your overall immunity levels are berries, citrus fruits, dark chocolate, red grapes, leafy greens, turmeric, elderberry, and ginger. These foods mentioned here support your immunity in numerous ways, so you should include them in your well-balanced diet when looking to boost your immunity levels. And it is recommended to avoid processed foods.

    Q) What are the worst foods that you should avoid to help support your overall immune health?

    A) Some of the worst foods that you should avoid eating to help support your overall immune health are: foods with added sugars, junk, and fast food, foods that contain artificial trans fats, refined carbs (which include white bread, pasta, pastries, cookies, and cakes) alongside processed meat. According to several research studies, you should always avoid the above foods to support your long-term immune health.

    Q) What are some of the best ways through which I can strengthen my immune system?

    A) As mentioned before, there is no comparison between a healthy lifestyle and a healthy, nutrient-rich, and fulfilling diet. One of the critical ways to fortify your immune system from within is to adopt a healthy lifestyle and solid dietary habits that support your immunity.

    RELATED:Best Magnesium Supplements to Use for Sleep, Anxiety and Weight Loss

    Affiliate Disclosure:

    The links contained in this product review may result in a small commission if you opt to purchase the product recommended at no additional cost to you. This goes towards supporting our research and editorial team and please know we only recommend high quality products.


    Please understand that any advice or guidelines revealed here are not even remotely a substitute for sound medical advice from a licensed healthcare provider. Make sure to consult with a professional physician before making any purchasing decision if you use medications or have concerns following the review details shared above. Individual results may vary as the statements made regarding these products have not been evaluated by the Food and Drug Administration. The efficacy of these products has not been confirmed by FDA-approved research. These products are not intended to diagnose, treat, cure or prevent any disease.

    The news and editorial staff of Sound Publishing, Inc. had no role in the preparation of this post. The views and opinions expressed in this sponsored post are those of the advertiser and do not reflect those of Sound Publishing, Inc.

    Sound Publishing, Inc. does not accept liability for any loss or damages caused by the use of any products, nor do we endorse any products posted in our Marketplace.

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